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OCR: Patients have normal serum calcium ate concentrations with a low serum phosp sphate concentration due to increased urine pl usually excretion, Serum alkaline phosphatase amin D increased. The plasma 1,25-dihydroxyvi ropriately concentration may be decreased or inap aemia, it normal. In the presence of hypophosph ailure of should be increased. The reason for this enal increase in 1-hydroxylase activity in the fect is tubular cells is unexplained. The basic d phosphate depletion due to renal tubula on dysfunction, and therapy for this condit amin D involves use of oral phosphate and a vi ondition metabolite. The clinical features of this teomalacia. are very similar to those of oncogenic o See also: . Imaging in Parathyroid/bone Disease